MOSAIC fuses wastewater, genomic, and outbreak-news signals into a single calibrated outbreak posterior, giving epidemiologists a population-scale early warning weeks before clinical case data catches up.
No signup. Real CDC NWSS data.
94%
P(Rt>1)
1.55
Rt
91d
lead
SARS-CoV-2
85
Influenza A
14
Influenza B
19
RSV
18
The mission
By the time clinical cases confirm a wave, it is already underway. The pathogens are already in the sewers, and the variants are already in the sequence databases. MOSAIC reads all three independent signals at once and turns them into one number an epidemiologist can trust.
Viral activity levels from treatment-plant sewersheds, a population-scale signal that doesn't depend on who seeks care or gets tested.
Lineage frequencies tracked over time; a KL-divergence jump flags an emerging variant before it dominates.
NLP extracts pathogen, place and counts from official outbreak reports and clinician posts worldwide.
How it works
Each stream is scored independently, fused in a hierarchical Bayesian model, and calibrated so the probability means what it says. Every stage is inspectable in the console.
3 surveillance streams
anomaly scoring
hierarchical model
P(Rt > 1)
Six capabilities, one calibrated posterior.
Per-sewershed activity levels with BOCPD change-point detection and sustained-elevation flags.
Rolling lineage frequencies and divergence-based anomaly scores for emerging variants.
Structured epi events extracted from WHO DON and ProMED with novelty detection.
A hierarchical model combines the streams into a single fused outbreak posterior, P(Rt>1).
Isotonic calibration so a stated 70% means 70%, validated across four historical outbreaks.
Auto-generated, per-site situation reports an epidemiologist can act on in minutes.
Validated, not vibes
MOSAIC was back-tested on real CDC NWSS records across Omicron, mpox, polio and H5N1. The headline result: well-calibrated probabilities with a meaningful early-warning lead.
0.086
Expected calibration error
ECE < 0.10 ⇒ well-calibrated
0.917
AUROC
strong growth discrimination
68 d
Median lead time
ahead of clinical confirmation
1,334
Day-ahead forecasts
real CDC NWSS record, 2021-25


Explore sewershed sites across the globe, fused posteriors, live WHO/ProMED outbreak news, lineage mixes, auto-generated briefings, and a built-in Claude assistant. No signup required.
Launch the live demo